Design changes are an enviable thing and happen constantly. If you work on placing all your rooms so that the center of the room object (where the two legs of the X intersect themselves) at or near the center of your room, you will always have a starting point at which to start searching for your room should you need to move it or adjust it.
This little tip can save you a little bit of time and frustration, plus it standardizes one more thing. Implement this procedure across everyone who works on your model and you can increase your teams efficiency because everyone will know exactly where to go to accomplish something.